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ADMET Bio-Tense Bio Reactor Testing Machine

ADMET - Bio-Tense Bio Reactor Testing Machine

Universal Testing Machine Accessories ( ADMET )

ADMET Bio-Tense Bioreactor Testing Machine: Advanced Instrument for Mechanobiology Research

The ADMET Bio-Tense Perfusion Bioreactor is an advanced testing instrument designed specifically for tissue engineers and cell biologists to conduct high-resolution investigations in Mechanobiology. This next-generation device is engineered to provide precise and reproducible results, making it an indispensable tool for cutting-edge biological research.

Compatibility with Inverted Microscopes: The Bio-Tense bioreactor is designed to integrate seamlessly with the XYZ stage of an inverted microscope, allowing for real-time observation of biological processes.

Advanced Capabilities: Enables researchers to study a variety of complex biological phenomena, including:

    • Fibroblast population growth, confluence, and stratification on diverse substrates.
    • Organized and complex cell sheet motions.
    • Coordinated extracellular matrix (ECM) production.
    • Customizable Design: As with all ADMET testing systems, the Bio-Tense bioreactor can be customized to meet the specific requirements of individual research projects.

This machine has already demonstrated its effectiveness in revealing critical insights into cell growth, ECM production, and motion dynamics, paving the way for advancements in biological science.

Category:

bio reactor testing machine, mechanobiology testing system, tissue engineering bioreactor, ADMET Bio-Tense, cell biology research instruments, customized bioreactor systems, extracellular matrix production, fibroblast growth studies.

ADMET Bio-Tense Bio Reactor Testing Machine Overview

The ADMET Bio-Tense Bio Reactor Testing Machine is an advanced testing system tailored for evaluating biomaterials’ mechanical properties under realistic physiological conditions. It is designed to simulate environments such as body temperature and humidity, ensuring accurate and reliable results for biomedical research and development.

This versatile system supports a wide range of tests, including tension, compression, and cyclic loading, making it ideal for analyzing soft tissues, scaffolds, hydrogels, and implantable medical devices. With ADMET’s MTEST Quattro Controller & Software, users benefit from precise control over testing parameters and real-time monitoring of results.

Compact in design and fully customizable, the Bio-Tense Bio Reactor enhances research efficiency while ensuring the reliability and performance of biomaterials for critical applications.

ADMET Bio-Tense Bio Reactor Testing Machine Features
  • Specialized Testing for Biomaterials: The ADMET Bio-Tense Bio Reactor is designed specifically for testing biomaterials, tissues, and medical devices, making it an essential tool for research in biomedical engineering and life sciences.
  • Dynamic Mechanical Stimulation: The system provides precise mechanical stimulation, including tension, compression, and shear, to mimic physiological conditions, ensuring realistic testing of biomaterials and tissue samples.
  • Temperature and Humidity Control: Integrated environmental controls allow for accurate temperature and humidity regulation, replicating in-vivo conditions for reliable and biologically relevant test results.
  • User-Friendly Interface: The Bio-Tense comes with an intuitive interface for easy operation, allowing researchers to set and adjust parameters such as load, strain, and displacement with minimal effort.
  • High-Precision Load and Displacement Sensors: Equipped with advanced sensors, the system ensures accurate measurements of force and displacement, critical for testing the mechanical properties of delicate biomaterials.
  • Customizable Test Protocols: Users can create and save custom test protocols, providing flexibility for various applications, including tissue engineering, scaffold testing, and medical device validation.
  • Real-Time Data Monitoring: The machine supports real-time data acquisition and display, allowing researchers to monitor specimen behavior and adjust test conditions dynamically as needed.
  • Compact and Modular Design: Its space-efficient, modular design ensures easy integration into laboratory setups and allows for upgrades or modifications to accommodate evolving research needs.
  • Compliance with Biomedical Standards: The Bio-Tense system meets industry standards for biomedical testing, ensuring reliable data for regulatory submissions and academic publications.
  • Versatile Applications: Suitable for testing a wide range of biomaterials, including soft tissues, hydrogels, and implants, as well as mechanical properties of scaffolds and medical devices.
  • Seamless Software Integration: The testing system integrates seamlessly with ADMET’s MTEST Quattro software, providing advanced data analysis, test automation, and reporting capabilities.
  • Automated Test Execution: Features automated test execution for consistent, repeatable results, minimizing manual intervention and operator variability.
  • Durable and Low-Maintenance: Built with high-quality materials and components, the Bio-Tense machine is durable and requires minimal maintenance, ensuring long-term reliability in laboratory environments.
  • Remote Monitoring and Control: The system supports remote access, enabling researchers to monitor and control experiments from different locations for enhanced flexibility and collaboration.

The ADMET Bio-Tense Bio Reactor Testing Machine is an advanced solution tailored to the needs of biomedical research, offering precise control, reliable data acquisition, and customizable features for a variety of applications in tissue engineering, material science, and medical device development.

ADMET Bio-Tense Bio Reactor Testing Machine Specifications:
  • The ADMET Bio-Tense is a specialized bioreactor testing machine designed for precise mechanical testing of biological tissues, biomaterials, and engineered constructs under controlled environmental conditions. It provides reliable and repeatable results essential for research and development in biomechanics and biomedical engineering.
  • Load Capacity: Configurable up to 500N, suitable for low-force biological testing applications.
  • Displacement Resolution: High-resolution linear actuators ensure precise positioning and movement for tension, compression, and cyclic loading.
  • Temperature Control: Integrated environmental chamber maintains physiological temperatures (typically 37°C ± 0.1°C) for accurate in-vitro testing.
  • Media Compatibility: Designed to work with saline or other physiological media to replicate in-vivo conditions.
  • Dual Actuator System: Enables multi-directional loading, including tensile and compressive testing.
  • Digital Controller: Integrated with ADMET’s MTEST Quattro software for customized test protocols, real-time monitoring, and advanced data analysis.
  • Force Measurement Accuracy: ± 0.5% of reading, down to 1/500th of full capacity.
  • Displacement Range: Configurable based on sample dimensions and testing requirements.
  • Testing Modes: Tension, compression, and cyclic fatigue tests.
  • Data Acquisition Rate: Up to 1 KHz for high-resolution test data.
  • Material Compatibility: Suitable for testing biological tissues, hydrogels, and soft polymers.
  • Fixture Compatibility: Compatible with various grips and fixtures to hold delicate specimens securely without damage.
  • Environmental Chamber: Stainless steel construction for durability and ease of sterilization.
  • Testing of biological tissues such as tendons, ligaments, and skin samples.
  • Biomechanical testing of engineered tissue scaffolds and biomaterials.
  • Fatigue and tensile testing of medical devices like sutures and meshes.
  • Research in regenerative medicine, biomechanics, and implant development.
  • Precision and Accuracy: Provides highly precise results for sensitive biomaterial testing.
  • Customizability: Test methods can be tailored to meet specific research goals or industry standards.
  • Ease of Use: User-friendly software and robust hardware ensure seamless operation.
  • Compliance: Performs tests in accordance with ASTM and ISO standards for biomedical testing.

The ADMET Bio-Tense Bio Reactor Testing Machine offers a comprehensive solution for researchers and manufacturers requiring meticulous mechanical testing in controlled biological environments.

ADMET Bio-Tense Bio Reactor Testing Machine Applications

The ADMET Bio-Tense Bio Reactor Testing Machine is a state-of-the-art system designed specifically for testing biological materials and soft tissues in controlled environments. It combines precise mechanical testing with a bioreactor environment, enabling researchers to evaluate the behavior and mechanical properties of biomaterials under physiologically relevant conditions.

Applications for Bio-Reactor Testing

  1. Tissue Engineering:

    • Used to assess the mechanical properties of engineered tissues, such as tensile strength, elasticity, and viscoelasticity.
    • Facilitates the growth and mechanical conditioning of tissues, mimicking the natural in vivo environment.

  2. Soft Tissue Testing:

    • Ideal for testing tendons, ligaments, skin, and other soft tissues to understand their mechanical behavior under stress, strain, and cyclic loading.
    • Enables the study of tissue failure modes, durability, and repair mechanisms.

  3. Biomechanical Research:

    • Supports research in biomechanics by providing real-time data on the performance of biological specimens under various load conditions.
    • Used for investigating the effects of mechanical stimulation on cell growth and differentiation.

  4. Medical Device Testing:

    • Evaluates the performance and durability of medical devices such as sutures, stents, and implants in a bioreactor environment.
    • Ensures compliance with regulatory standards for safety and performance.

  5. Pharmaceutical Research:

    • Used to test drug-eluting implants and their mechanical behavior in a simulated biological environment.
    • Assesses the impact of pharmaceuticals on the mechanical integrity of tissues or biomaterials.

  6. Hydrogel and Scaffold Testing:

    • Ideal for testing hydrogels, scaffolds, and other biomaterials used in regenerative medicine.
    • Measures properties like stiffness, strength, and degradation over time under simulated physiological conditions.

  7. Vascular Tissue Testing:

    • Enables the testing of arteries, veins, and other vascular tissues for mechanical properties like compliance, burst pressure, and fatigue resistance.
    • Essential for designing vascular grafts and testing their performance.

  8. Cartilage and Bone Research:

    • Allows for mechanical testing of cartilage and bone tissues, focusing on stress-strain relationships, compression, and fracture properties.
    • Useful for studying osteoarthritis, osteoporosis, and other musculoskeletal disorders.

  9. Dynamic Loading Studies:

    • Simulates cyclic loading conditions to evaluate the fatigue resistance and viscoelastic properties of biomaterials and soft tissues.
    • Supports long-term durability studies.

  10. In-Vitro Simulation of Physiological Conditions:

    • Simulates the natural biological environment, including temperature, humidity, and fluid flow, to test the mechanical behavior of materials under realistic conditions.
Advantages of ADMET Bio-Tense Bio Reactor Testing Machine
  • Precision Control: Offers precise control of load, displacement, and strain, ensuring accurate and repeatable test results.
  • Integrated Bioreactor Environment: Provides physiological conditions, such as temperature and fluid flow, to mimic in vivo conditions.
  • Customizable Test Profiles: Supports a wide range of test configurations, including tensile, compressive, and fatigue testing.
  • Real-Time Data Acquisition: Captures high-resolution data for detailed analysis of mechanical properties and performance.
  • User-Friendly Software: Intuitive interface for setting up tests, monitoring progress, and analyzing results.
  • Versatile Sample Compatibility: Can accommodate various specimen types, including tissues, biomaterials, and medical devices.
  • Durability Testing: Enables long-term studies to assess the lifespan and degradation of biomaterials.
  • Compact Design: Space-efficient system suitable for laboratory environments.
Industry Applications
  • Biomedical Research:
    • Tissue engineering, soft tissue mechanics, and biomaterial development.
  • Healthcare & Medical Device Testing:
    • Testing medical implants, sutures, and prosthetics under simulated biological conditions.
  • Pharmaceutical Development:
    • Evaluating drug delivery systems and their interaction with tissues.
  • Academic Research:
    • Supporting studies in biomechanics, regenerative medicine, and bioengineering.
  • Regenerative Medicine:
    • Developing and testing scaffolds, hydrogels, and other biomaterials for tissue regeneration.

The ADMET Bio-Tense Bio Reactor Testing Machine is an indispensable tool for researchers and industries focused on the mechanical testing of biomaterials and soft tissues. By integrating advanced mechanical testing capabilities with a bioreactor environment, it enables comprehensive analysis and innovation in biomedical research, tissue engineering, and medical device development.

1. What is the ADMET Bio-Tense Bio Reactor Testing Machine?

The ADMET Bio-Tense Bio Reactor Testing Machine is a specialized system designed for conducting tensile, compressive, and dynamic mechanical testing on biological tissues and biomaterials. It is ideal for applications such as mechanical property characterization, tissue engineering, and biomedical research.

The Bio-Tense Bio Reactor is designed to test a variety of biological tissues and biomaterials, including:

  • Tendons
  • Ligaments
  • Skin
  • Cartilage
  • Blood vessels
  • Soft tissues
  • Synthetic biomaterials used in medical devices

Key features include:

  • Controlled environmental chamber to simulate physiological conditions (e.g., temperature, humidity, and pH levels).
  • Precision load and displacement measurement for accurate mechanical property testing.
  • Dynamic testing capabilities, including cyclic loading and stress-relaxation tests.
  • Adjustable grips and fixtures for accommodating various sample sizes.

Real-time data acquisition and analysis software for seamless operation.

The system supports a range of testing modes, including:

  • Tensile testing
  • Compression testing
  • Dynamic mechanical analysis
  • Stress-relaxation tests
  • Creep testing
  • Fatigue testing

These modes enable comprehensive evaluation of biological tissues under various mechanical conditions.

The Bio-Tense Bio Reactor is equipped with an environmental chamber that maintains controlled conditions such as:

  • Temperature: Mimics body temperature for accurate testing (typically 37°C).
  • Humidity: Prevents tissue dehydration during testing.

Fluid circulation: Allows the use of nutrient-rich solutions to keep biological samples viable during extended tests.

The Bio-Tense Bio Reactor is widely used in:

  • Biomedical research
  • Tissue engineering
  • Regenerative medicine
  • Orthopedics (e.g., ligament and tendon studies)
  • Medical device testing

Pharmaceutical development (e.g., drug delivery materials testing)

Yes, the Bio-Tense Bio Reactor integrates seamlessly with other ADMET material testing systems. It can share software and control platforms, making it a versatile addition for labs already equipped with ADMET systems.

Benefits include:

  • Accurate simulation of in vivo conditions for reliable results.
  • Comprehensive mechanical analysis of biomaterials.
  • Customizable fixtures and grips for diverse testing applications.
  • Ease of use with intuitive software and real-time monitoring.

High repeatability and precision, ensuring consistency across tests.

The system comes with ADMET’s advanced testing software, which provides:

  • Test protocol customization for different materials.
  • Real-time data logging and graphical test monitoring.
  • Automated report generation for documentation.

Integration with external sensors for additional measurements.

Yes, the Bio-Tense Bio Reactor supports dynamic testing, including:

  • Cyclic loading and unloading
  • Fatigue testing to assess long-term durability

Stress-relaxation and creep testing for time-dependent material behavior

The load capacity varies depending on the configuration but is typically designed to handle low-force applications suitable for biological tissues, ensuring precise and sensitive measurements.

To maintain optimal performance:

  • Regularly clean the environmental chamber and testing fixtures.
  • Calibrate the load and displacement sensors periodically.
  • Inspect grips and fixtures for wear and replace if necessary.

Update software to the latest version for improved functionality.

The Bio-Tense Bio Reactor stands out due to its:

  • Ability to mimic physiological conditions accurately.
  • Specialized design for testing sensitive biological samples.
  • Compatibility with various testing modes for comprehensive analysis.
  • User-friendly interface for simplified operation.

Yes, ADMET offers customization options for the Bio-Tense Bio Reactor, including:

  • Tailored grips and fixtures for unique sample geometries.
  • Customizable software protocols for specific testing requirements.
  • Integration with additional sensors or devices for enhanced data collection.

The Bio-Tense Bio Reactor typically includes a one-year warranty, covering manufacturing defects and hardware issues. Extended warranties and service plans may also be available.

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